5 edition of New Approaches to Drug Development (Experientia Supplementum) found in the catalog.
October 2, 2000
by Birkhäuser Basel
Written in English
|The Physical Object|
|Number of Pages||252|
Commonly Used Drugs - Uses, Side Effects, Bioavailability & Approaches to Improve it Book January with , Reads How we measure 'reads'Author: Rafik Karaman. New Approaches to Drug Development. edited by P. Jollès, Birkhäuser Verlag, Basel, Switzerland, ( pages) ISBN 3 8. This book provides a good overview on various challenging areas of new drug development. Emphasis is laid on new types of active agents and strategies that were made possible owing to recent advances in Author: Juergen Siepmann.
Aspects of the drug patent system impede the development of first-in-class drugs and reward the development of follow-on drugs (subsequent class entrants). Public subsidies of basic research and phase III clinical trials, as well as impact-based and royalty-based rewards for new drugs are promising alternatives to the drug patent by: Each approach to drug treatment is designed to address certain aspects of drug addiction and its consequences for the individual, family, and society. This section presents examples of treatment approaches and components that have an evidence base supporting their use. Each approach is designed to address certain aspects of drug addiction and its consequences for the individual, .
Challenges with the traditional phased drug development paradigm in the age of targeted therapies and opportunities for using new approaches to cancer therapy development and regulatory review. Best practices for cancer drug development and review (e.g., trial design, statistical approaches, ethical considerations and informed consent, industry. Drug discovery involves multiple disciplines, technologies, and approaches. This book selects important topics related to drug discovery, including emerging tool (Chapter 1), cutting-edge approaches (Chapters 2, 3, and 4), examples of specific therapeutic area (Chapter 5), quality control in drug development (Chapter 6), and job and career opportunities in the Cited by: 1.
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This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug.
The traditional pharmaceutical research and development process suffers from a high attrition rate. For every new drug brought to the market, most estimates suggest that researchers will typically have employed over screens looking for drug leads, winnowing down from tens of thousands of compounds (Figure ).Lead discovery research is also costly and time.
ISBN: OCLC Number: Description: xi, pages: illustrations ; 24 cm. Contents: The impact of genomics on therapeutic drug development / Giulia C. Kennedy --Regulation of mammalian gene expression / Detmar Beyersmann --New trends in antimicrobial development / Eduardo L.
Setti and Ronald G. New Approaches in Cancer Pharmacology: Drug Design and Development (Springer Series in Solid-State Sciences) Workman, P. Published by Springer-Verlag Telos (). Book Description. Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace.
It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and.
The topics cover the different parts of the drug discovery process, starting with new developments in the target identification and validation area. The lead generation part as a next step focuses on the requirements and technologies to identify new small molecules as lead compounds for further optimization; in a second section the technologies.
Network biology and polypharmacology approaches gained appreciation recently as methods for omics data integration and multitarget drug development, respectively. The combination of these two approaches created a novel paradigm called network pharmacology (NP) that looks at the effect of drugs on both the interactome and the diseasome level.
Open Library is an open, editable library catalog, building towards a web page for every book ever published. New Approaches in Cancer Pharmacology: Drug Design and Development by Paul Workman, Henning Genz, Massimo Malvetti, James Dodd; 1 edition.
The development of new drugs is very complex, costly and risky. Its success is highly dependent on an intense collaboration and interaction between many departments within the drug development organization, external investigators and service providers, in constant dialogue with regulatory authorities, payers, academic experts, clinicians and patient.
Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers.
Case histories and lessons from successful and unsuccessful applications of biomarkers are included along with key. Understanding Tuberculosis - New Approaches to Fighting Against Drug Resistance. Edited by: Pere-Joan Cardona. ISBNPDF Cited by: This book presents principles underlying preclinical and clinical development of new therapeutic drugs and describes and evaluates specific examples, and discusses legal and ethical regulations that apply to drug development.
ISBN: OCLC Number: Description: pages: illustrations ; 29 cm. Contents: Sequence and gene-specific drugs / M. D'Incalci, M. Broggini and J.A. Hartley --Antisense and antigene oligonucleotides targeted to oncogenes / C. Hélène --Prospects for biological and gene therapies / K.
Sikora and A. In Cancer Drug Resistance, leading scientists from the best academic institutions and industrial laboratories summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to a wide variety of anticancer therapeutics, as well as suggest new approaches to the biology of drug Format: Hardcover.
Early chapters describe the basic principles of the subject and the later ones go on to illustrate how these principles are applied in the modern approaches to drug development and clinical drug use.
The book has been arranged to take the reader on a journey from a brief introduction to largely qualitative descriptions of drug disposition. New Approaches in Cancer Pharmacology: Drug Design and Development the rate of technological development that impinges on the diagnosis and treatment of cancer has been so rapid that it is not an easy task for medical faculties to adapt their curricula flexibly.
With its residential courses for organ pathologies and the seminars on new. Pharmacokinetic and Pharmacodynamic Variability. Pharmacogenetics and Dose Response: Dose Individualization. Optimal Dose Finding in Drug Development: Approaches and Regulatory Perspectives.
Optimal Dose Selection in Drug Development: Role of Population Pharmacokinetics in Phase 3. Dose Optimization Strategy for Strattera, A CYP2D6 Substrate.
COMMUNITY DEVELOPMENT APPROACHES 51 nia, members of a REACH community worked with the city council to establish a moratorium on new fast-food restaurants in south central Los Angeles. When you mobilize communities, Giles said, they are empowered to approach policy makers about these issues.
introduced by firms into altogether new product categories approaches 50%. Without a good new product development (NPD) process, firms can lose the significant investments in research and development, engineering, marketing research, and testing that are made on products/ideas that never return Size: KB.
This book provides a road map of the current drug development process and how computational biology approaches play a critical role across the entire drug discovery pipeline.
Through the use of previously unpublished, real-life case studies the impact of a range of computational approaches are discussed at various phases of the pipeline/5(6). The book "Nanocosmetics and nanomedicines: new approaches for skin care” contains a summary of the most important nanocarriers for skin delivery.
Although “nanocosmetics” is a subject widely commented in the academy and the beauty industry, a book covering the skin care treatments using.Given the long gap in the introduction of new structural classes of antibiotics—38 years between streptogramins in and linezolid in (Walsh a,b)—and the inexorable development of resistance to a given antibiotic once it is in widespread clinical use, there is a pressing and recurrent need for new molecules with antibiotic.Purchase Innovative Approaches in Drug Discovery - 1st Edition.
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